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Test tests (LFT) Frequency • • clozapine requires much more frequent monitoring of FBC (initially weekly) at the start of therapy at 3 months annually at the start of therapy at 6 months annually • • Lipids, weight • • • • • • • • low-dose amitriptyline is commonly used in the management of neuropathic pain and the prophylaxis of headache (both tension and migraine) lofepramine has a lower incidence of toxicity in overdose amitriptyline and dosulepin (dothiepin) are considered the most dangerous in